Abstract: Polymeric blends were prepared via melt mixing from polyamide 6 (PA6) and glycerol plasticized thermoplastic starch (TPS). The influence of glycerol on the property of PA6/TPS blends was investigated, and the toughening mechanism of the blends was explored as well. By adding TPS, the impact strength and the tensile modulus of the blends increased, while the tensile strength and the melt flow rate slightly declined, which revealed that TPS acted as rigid particles. The scanning electron microscope (SEM) images for the impact fractured surface of the samples suggested that the main toughing mechanism of PA6/TPS blends was the interfacial voiding effect. In addition, the content of glycerol and TPS played a notable role in the toughening effect. When the TPS content was 25 %, the impact strength was increased by 630 % based on neat PA6.