Abstract: This paper overviewed the development of electron beam irradiation and its application for radiation-resistant modification of polymeric materials, and its limitation in utilization for bulk irradiation resistant polymer materials was emphasized. This paper also introduced research results in incorporation of large electron cloud, hindered phenolic antioxidants, and effect of hindered amine light stabilizers on irradiation properties of polymeric materials as well as the use and effectiveness of other radiationresistant modifiers. It was concluded that the addition of hindered phenolic antioxidants and hindered amine light stabilizers could enhance the radiation resistance of polymeric materials to some extent, and combination of different stabilizers could achieve a much better radiation-resistant effect on polymeric materials. In this case, the development of highly efficient stabilizers will be an urgent issue for the preparation of radiation-resistant polymers.