Abstract: Mixture design is a very useful method to solve the problems in formulation determination of materials. This paper introduced the applications of mixture design in the formulation design for two polypropylene (PP)-based automotive materials, FL-TD20 and JL-TD20, by means of the Minitab statistical software.An effective regression equation of melt flow rate was deduced for FL-TD20 product. As for the mixture design of JL-TD20 product, three components were found to have no significant influence on the density and ash content of PP compounds, and however therewasa remarkable effect from them on the melt flow rate, notchedimpact strength, tensile strength, thermal deformation temperature and bending strength of the compounds. The regression equation based on five performance indexes was deduced, andthe ranges of qualified formulations based on performance indexeswere further determined. The predicted values were found to have the differences less than 5 % according to the validation of experimental results.