Abstract: The types of mesoporous silica materials and synthetic methods were introduced and the research status of hemostatic materials based on mesoporous silica was reviewed. These hemostatic materials included mesoporous silica materials, the combination of mesoporous silica and organic materials, the combination of mesoporous silica and metal ion materials, and they demonstrated the good hemostatic and antibacterial properties due to the use of mesoporous silica. Finally, the prospect in the application of mesoporous silica combined with other materials for hemostasis applications was discussed.