Abstract: The safety of food packing material has attracted a great deal of attention from the publics. The utilization of a risk assessment for the migrant is considered as an effective method to ensure human health. The exposure assessment plays an important role in risk assessment of food safety. There are many methods for conducting exposure assessment, which include deterministic approach and probabilistic approaches. Through the introduction and comparison of these two types of approaches, some appropriate methods are selected by using the theory of tiered approaches for exposure assessment. The deterministic approaches including EU, FDA and refined deterministic approaches are superior due to the feasibility and simplification. When the result of deterministic approach cannot judge the effect of exposure assessment, the probabilistic approach can be applied for the further process. Probabilistic approach can get more accurate exposure results, and however it requires more data as well as an available model.