Abstract: poly(sebacic acid -glycery monolaurate) was synthesized with sebacic acid and glycery monolaurate using tetrabutyl titanate as catalyst. The polyester was characterized by gel permeation chromatography (GPC), nuclear magnetic response spectroscopy (1HNMR) and fourier transform infrared spectroscopy(FT IR). The blend of the polyester and poly(vinyl chloride)(PVC) was Thermoplastic molding. The mechanical properties and the thermodynamic properties of the blends were characterized using thermogravimetric analysis(TG), differential scanning calorimetry(DSC) and universal tensile testing machine. The results showed that the polyester could improve the thermal stability and reduce the glass transition temperature of PVC, the excellent mechanical and thermal PVC products will be prepared by using polyester and phthalate as mixed plasticizer.