Abstract: In this work， a series of poly（butanediol adipic ester） ［P（BS-co-BA）］ copolyesters were synthesized by using 1，4-butanediol， adipic acid， and succinic acid as raw materials， and their structures and properties were characterized and analyzed by using attenuated total reflection Fourier-transform infrared spectrometer， nuclear magnetic resonance instrument， differential scanning calorimeter， X-ray diffractometer， and thermogravimetric analyzer. The keratin enzyme degradation results indicated that the four copolyesters reached more than 80 wt% after reacting16 h， but the two homopolyesters only reached about 40 wt%. The degradation rate of polyester enzyme increased by a order of P（BS-co-40 % BA） > P（BS-co-60 % BA） > P（BS-co-80 % BA） > P（BS-co-20 % BA） > poly（butylene adipate） （PBA） > poly（butylene adipate） （PBS）. The thermal stability and degradation performance of P（BS-co-40 % BA） were both better than those of pure PBA， indicating that P（BS-co-40 % BA） is an optimal product with the best performance.

Key words: copolyester, poly（butylene succinate）, poly（butylene adipate）, enzymatic degradation