Preparation of Silver Nanoparticle via Hydrophilic Random Copolymers and Its Antibacterial Application

doi:10.19491/j.issn.1001-9278.2020.11.003

Abstract

Abstract:

A self?assembled system was prepared using pure hydrophilic random copolymer poly（DMAEMA-co-AA） as a template， and its morphology and structure were investigated. Silver nanoparticles were then prepared by an in-situ reduction method， and their application in antibacterial packaging was studied. The results indicated that the pure hydrophilic random copolymer poly（DMAEMA-co-AA） could form the stable structures of microporous rod-like and rod?like secondary self-assembled systems in spherical or cubic shape at low pH value. With the increase of silver reduction rate， the silver nanoparticles disintegrated from the spherical or cubic shape to a small spherical shape. The logarithm antibacterial value of the antibacterial film was more than 4.5. The storage time of fruits at room temperature increased by more than 4 times after the silver nanoparticles were used for antibacterial packaging.

Key words: hydrophilic random copolymer, aqueous self?assembly, antibacterial material, silver nanoparticle

CLC Number:

TQ325.1⁺4

YANG Lu, CHEN Hanting. Preparation of Silver Nanoparticle via Hydrophilic Random Copolymers and Its Antibacterial Application[J]. China Plastics, 2020, 34(11): 12-18.

Figures/Tables 8

References 23

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DMAEMA∶AA (mol/mol)	AA含量/%	M_n/10⁴	M_w/10⁴	多分散系数
30∶70	51.6	2.37	2.79	1.18
70∶30	16.6	1.83	2.11	1.15

DMAEMA∶AA (mol/mol)	AA含量/%	M_n/10⁴	M_w/10⁴	多分散系数
30∶70	51.6	2.37	2.79	1.18
70∶30	16.6	1.83	2.11	1.15

序号	测试菌种	菌种浓度/×10⁷ cfu·mL^-1	回收菌种浓度/cfu?cm^-2			对数抗菌值R
序号	测试菌种	菌种浓度/×10⁷ cfu·mL^-1	样品	接触时间为0 h	接触时间为24 h	对数抗菌值R
1	大肠杆菌ATCC 8739	2.6	F1	—	9.2×10²	4.513 3
	大肠杆菌ATCC 8739	2.6	对照样品	2.3×10⁶	3.0×10⁷	—
	金黄色葡萄球菌 ATCC 6538P	2.3	F1	—	6.3×10²	4.562 4
	金黄色葡萄球菌 ATCC 6538P	2.3	对照样品	2.3×10⁶	2.3×10⁷	—
2	大肠杆菌ATCC 8739	2.4	F2	—	5.7×10²	4.706 5
	大肠杆菌ATCC 8739	2.4	对照样品	2.5×10⁶	2.9×10⁷	—
	金黄色葡萄球菌 ATCC 6538P	2.3	F2	—	4.4×10²	4.678 8
	金黄色葡萄球菌 ATCC 6538P	2.3	对照样品	2.1×10⁶	2.1×10⁷	—
3	大肠杆菌ATCC 8739	2.5	F3	—	4.9×10	5.671 5
	大肠杆菌ATCC 8739	2.5	对照样品	2.8×10⁶	2.3×10⁷	—
	金黄色葡萄球菌 ATCC 6538P	2.5	F3	—	8.3×10	5.495 9
	金黄色葡萄球菌 ATCC 6538P	2.5	对照样品	2.6×10⁶	2.6×10⁷	—

序号	测试菌种	菌种浓度/×10⁷ cfu·mL^-1	回收菌种浓度/cfu?cm^-2			对数抗菌值R
序号	测试菌种	菌种浓度/×10⁷ cfu·mL^-1	样品	接触时间为0 h	接触时间为24 h	对数抗菌值R
1	大肠杆菌ATCC 8739	2.6	F1	—	9.2×10²	4.513 3
	大肠杆菌ATCC 8739	2.6	对照样品	2.3×10⁶	3.0×10⁷	—
	金黄色葡萄球菌 ATCC 6538P	2.3	F1	—	6.3×10²	4.562 4
	金黄色葡萄球菌 ATCC 6538P	2.3	对照样品	2.3×10⁶	2.3×10⁷	—
2	大肠杆菌ATCC 8739	2.4	F2	—	5.7×10²	4.706 5
	大肠杆菌ATCC 8739	2.4	对照样品	2.5×10⁶	2.9×10⁷	—
	金黄色葡萄球菌 ATCC 6538P	2.3	F2	—	4.4×10²	4.678 8
	金黄色葡萄球菌 ATCC 6538P	2.3	对照样品	2.1×10⁶	2.1×10⁷	—
3	大肠杆菌ATCC 8739	2.5	F3	—	4.9×10	5.671 5
	大肠杆菌ATCC 8739	2.5	对照样品	2.8×10⁶	2.3×10⁷	—
	金黄色葡萄球菌 ATCC 6538P	2.5	F3	—	8.3×10	5.495 9
	金黄色葡萄球菌 ATCC 6538P	2.5	对照样品	2.6×10⁶	2.6×10⁷	—

[1]	YANG Lu, CHEN Hanting. Study on pH⁃dependent Self⁃Assembly Behavior of Purely Hydrophilic Random Copolymers for Controlled Release of Active Substances [J]. China Plastics, 2020, 34(9): 9-15.
[2]	YANG LU, CHEN Hanting . Fabrication of Antibacterial Nanomaterials via Pure Hydrophilic Self⁃assembly [J]. China Plastics, 2020, 34(10): 12-17.