Abstract: Chitosan-based intelligent hydrogels including temperature sensitive, pH sensitive, and temperature/pH sensitive types were summarized with their merits and shortcomings analyzed. The applications of the chitosan-based hydrogels in drug releasing and organization engineering were reviewed. Finally, the current problems and future development of chitosan-based hydrogels were presented.

Key words: intelligent hydrogel, chitosan, temperature sensitive, pH-sensitive, drug release, tissue engineeing