Preparation of poly （L⁃lactic acid）/chitosan films through UV curing and their thermal， mechanical and antibacterial properties

doi:10.19491/j.issn.1001-9278.2023.08.006

Abstract

Abstract:

A low molecular⁃weight poly（L⁃lactic acid）（PLLA） and poly（icconic acid⁃co⁃butanediol）（PBI） were first synthesized， and the resulting two copolymers were mixed to obtain high molecular weight poly （L⁃lactic acid co⁃icconic acid⁃co⁃butanediol）（PLBI） through a polycondensation reaction. Then， chitosan （Cs） was grafted with glycidyl methacrylate （GMA） to obtain a GMA⁃grafted chitosan copolymer （Cs⁃g⁃GMA） with double bond groups. Finally， the resulting Cs⁃g⁃GMA and PLBI films were laminated through UV curing to obtain a PLBI/Cs⁃g⁃GMA bacteriostatic film with covalent bonds at the interface. NMR analysis indicated that PLBI and Cs⁃g⁃GMA copolymers were successfully prepared. The infrared spectroscopic analysis of the PLBI/Cs⁃g⁃GMA film demonstrated that Cs⁃g⁃GMA_{was successfully grated into the PLBI film. Mechanical test results indicated that the mechanical properties of PLBI film were significantly improved， and its elongation at break reached 214.3 %. Hydrophilic test results indicated that the hydrophilicity of the PLBI/Cs⁃g⁃GMA film was enhanced together with good cytocompatibility. The PLBI/Cs⁃g⁃GMA film exhibited a good antibacterial effect on escherichia coli with an antibacterial rate as high as 83.4 %.}

Key words: poly（lactic acid）, chitosan, UV irradiation, mechanical property, bacteriostasis

CLC Number:

TQ321

DU Le, HU Yajie, HU Jian, SUN Tao, YUN Xueyan, DONG Tungalag. Preparation of poly （L⁃lactic acid）/chitosan films through UV curing and their thermal， mechanical and antibacterial properties[J]. China Plastics, 2023, 37(8): 38-44.

Figures/Tables 9

References 29

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样品	T_g/ ℃	T_cc/ ℃	ΔH_cc/ J·g^-1	T_m/ ℃	△H_m/ J·g^-1	X_c/ %
PLBI	23.4	68.3	16.1	135.1	20.8	5.0
Cs⁃g⁃GMA	—	—	—	—	—	—
PLBI/Cs⁃g⁃GMA_0.4	23.2	66.4	16.4	134.5	21.5	5.4
PLBI/Cs⁃g⁃GMA_0.6	23.8	65.8	12.3	130.7	19.4	7.6
PLBI/Cs⁃g⁃GMA_0.8	23.7	65.3	12.4	130.1	20.5	8.7
PLBI/Cs⁃g⁃GMA_1.0	23.6	65.0	9.1	131.2	23.7	15.6

样品	T_g/ ℃	T_cc/ ℃	ΔH_cc/ J·g^-1	T_m/ ℃	△H_m/ J·g^-1	X_c/ %
PLBI	23.4	68.3	16.1	135.1	20.8	5.0
Cs⁃g⁃GMA	—	—	—	—	—	—
PLBI/Cs⁃g⁃GMA_0.4	23.2	66.4	16.4	134.5	21.5	5.4
PLBI/Cs⁃g⁃GMA_0.6	23.8	65.8	12.3	130.7	19.4	7.6
PLBI/Cs⁃g⁃GMA_0.8	23.7	65.3	12.4	130.1	20.5	8.7
PLBI/Cs⁃g⁃GMA_1.0	23.6	65.0	9.1	131.2	23.7	15.6

样品	厚度/μm	屈服强度/ MPa	断裂伸长率/%	弹性模量/ MPa
PLBI	48.0±0.8	6.1±0.3	214±13.8	197±2.0
PLBI/Cs⁃g⁃GMA_0.4	50.6±0.5	3.1±0.1	212±21.2	89±2.6
PLBI/Cs⁃g⁃GMA_0.6	50.2±1.4	2.1±0.6	114±12.6	92±7.1
PLBI/Cs⁃g⁃GMA_0.8	49.8±1.3	4.3±0.5	75±8.9	108±10.9
PLBI/Cs⁃g⁃GMA_1.0	50.2±1.1	5.9±1.3	67±2.9	140±11.2

样品	厚度/μm	屈服强度/ MPa	断裂伸长率/%	弹性模量/ MPa
PLBI	48.0±0.8	6.1±0.3	214±13.8	197±2.0
PLBI/Cs⁃g⁃GMA_0.4	50.6±0.5	3.1±0.1	212±21.2	89±2.6
PLBI/Cs⁃g⁃GMA_0.6	50.2±1.4	2.1±0.6	114±12.6	92±7.1
PLBI/Cs⁃g⁃GMA_0.8	49.8±1.3	4.3±0.5	75±8.9	108±10.9
PLBI/Cs⁃g⁃GMA_1.0	50.2±1.1	5.9±1.3	67±2.9	140±11.2

组别	水接触角/（°）	图像
PLBI	71.6±2.1
PLBI/Cs⁃g⁃GMA_0.4	46.6±1.2
PLBI/Cs⁃g⁃GMA_0.6	45.2±0.8
PLBI/Cs⁃g⁃GMA_0.8	44.6±1.0
PLBI/Cs⁃g⁃GMA_1.0	40.7±1.9