中国塑料 ›› 2023, Vol. 37 ›› Issue (9): 8-13.DOI: 10.19491/j.issn.1001-9278.2023.09.002

• 材料与性能 • 上一篇    下一篇

抗菌可降解聚乳酸薄膜制备与性能测试

关国涛1,4,5, 刘晨泽1, 何世权2, 宋超洋1, 张响1,4,5(), 赵娜1,4,5, 王超3()   

  1. 1.郑州大学力学与安全工程学院,郑州 450001
    2.郑州大学护理与健康学院,郑州 450001
    3.郑州四六零医院,郑州 450001
    4.国家级微纳成型技术国际联合研究中心,郑州 450001
    5.河南省微成型技术重点实验室,郑州 450001
  • 收稿日期:2023-03-20 出版日期:2023-09-26 发布日期:2023-09-18
  • 通讯作者: 张响(1978—),男,郑州大学力学与安全工程学院,教授,主要从事聚合物微成型、微流控与器官芯片研究,zhangxiang@zzu. edu.cn
    王超(1987-),男,郑州四六零医院口腔科,主治医师,主管技师,主要从事口腔修复临床工作以及口腔修复材料的临床应用与研究,495125983@qq.com
    E-mail:zhangxiang@zzu. edu.cn;495125983@qq.com

Preparation and properties of antibacterial biodegradable poly (lactic acid) membrane

GUAN Guotao1,4,5, LIU Chenze1, HE Shiquan2, SONG Chaoyang1, ZHANG Xiang1,4,5(), ZHAO Na1,4,5, WANG Chao3()   

  1. 1.School of Mechanics and Safety Engineering,Zhengzhou University,Zhengzhou 450001,China
    2.School of Nursing and Health,Zhengzhou University,Zhengzhou 450001,China
    3.No. 406 Hospital of Zhengzhou,Zhengzhou 450001,China
    4.National Center for International Joint Research of Micro?Nano Molding Technology,Zhengzhou 450001,China
    5.Key Laboratory for Micro Molding Technology of Henan Province,Zhengzhou 450001,China
  • Received:2023-03-20 Online:2023-09-26 Published:2023-09-18
  • Contact: ZHANG Xiang, WANG Chao E-mail:zhangxiang@zzu. edu.cn;495125983@qq.com

摘要:

将季铵盐与聚乳酸溶液共混并通过静电纺丝技术成功制备了抗菌可降解薄膜材料。利用扫描电子显微镜、电子万能材料试验机、纤维直径统计分布、抗菌性能测试等对纤维薄膜的结构和性能进行了表征。结果表明,单链季铵盐可在一定程度上提高聚乳酸薄膜材料的抗菌性能,但会降低薄膜的断裂强度和弹性模量。双链季铵盐能较大程度提高聚乳酸薄膜材料抗菌性能的同时保证薄膜材料具有良好的拉伸/断裂强度和延伸率,成膜均匀,抗菌剂分散性好,适于工业化生产和应用。

关键词: 季铵盐, 聚乳酸, 静电纺丝, 抗菌薄膜

Abstract:

In this study, an antibacterial degradable membrane was successfully prepared through electrostatic spinning using a mixture of quaternary ammonium salt and poly(lactic acid) (PLA), and their structure and properties were characterized by using scanning electron microscope, electronic universal material testing machine, statistical distribution of fiber diameter, and antibacterial property measurement. The results indicated that the single chain quaternary ammonium salt improve the antibacterial performance of the PLA membrane to a certain extent but reduced its breaking strength and elastic modulus. The double⁃chain quaternary ammonium salt improved the antibacterial performance of the PLA membrane significantly. This ensures that the membrane achieves high tensile/breaking strength and elongation, good membrane formation uniformity, and good dispersity of antibacterial agents. Therefore, the PLA membrane filled with the double⁃chain quaternary ammonium salt is more suitable for industrial production and practical applications.

Key words: quaternary ammonium salt, poly(lactic acid), electrospinning, antibacterial membrance

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