Research Progress in Poly ( lactic acid ) -poly ( ethylene glycol)Block Copolymers

Abstract

Abstract: The research work on poly(lactic acid)-polyethylene glycol) (PLA-PEG) block copolymers and its application as microsphere carriers were reviewed. The synthesis methods of PLA-PEG were described in details, including the polycondensation of lactide and PEG, the polycondensation of lactic acid and PEG, the polycondensation of lactide and ethylene oxide. The properties of PLA-PEG block copolymers and their applications in biomedical fields, such as drug delivery system, bone fixing, tissue repairing, and surgical mending~simply introduced. The prospect of these polymers was also discussed.

Key words: polyethylene glycol), poly(lactic acid), block copolymer

CLC Number:

TQ323 . 4

LIU Ji-san, LIANG Guo-zheng, ZHANG Zeng-ping, ZHANG Xuan, WANG Jiu-cheng, . Research Progress in Poly ( lactic acid ) -poly ( ethylene glycol)Block Copolymers[J]. China Plastics, 2007, 21(2): 1-4.

[1]	SHEN Xuemei, ZHU Xiaolong, HU Yanchao, SONG Renyuan, ZHANG Xianfeng, LI Xi. Fabrication and properties of poly（lactic acid））/ibuprofen microspheres through electrostatic spray method [J]. China Plastics, 2022, 36(7): 61-67.
[2]	SHAO Linying, XI Yuewei, WENG Yunxuan. Research progress in degradation characteristics of poly（lactic acid） composites [J]. China Plastics, 2022, 36(6): 155-164.
[3]	WANG Rongchen, ZHANG Heng, SUN Huanwei, DUAN Shuxia, QIN Zixuan, LI Han, ZHU Feichao, ZHANG Yifeng. Research progress in preparation and hydrophilic modification of polylactic acid nonwovens for medical and health applications [J]. China Plastics, 2022, 36(5): 158-166.
[4]	SUN Tao, YANG Qing, HU Jian, WANG Yangyang, LIU Bo, YUN Xueyan, DONG Tungalag. Preparation and properties of poly（lactic acid⁃co⁃glycolic acid） film [J]. China Plastics, 2022, 36(2): 33-40.
[5]	WEI Zongchen, XI Yuewei, WENG Yunxuan. Research Progress in Poly（lactic acid）⁃based Composite Materials for Bone Tissue Engineering [J]. China Plastics, 2021, 35(9): 136-146.
[6]	TANG Yujing, WANG Yaqiao, NI Jingyue, WANG Conglong, WANG Xiangdong. Effect of Stereoscopic Composite Crystals on Foaming Behavior of PLA [J]. China Plastics, 2021, 35(8): 117-124.
[7]	LI Yuzhu, YAO Lihui, YE Shiqiang, LYU Guoyong, LIU Panpan, XU Longfei, QIU Dan. Research Progress on Degradation Performance of Biodegradable Materials in Water Environment [J]. China Plastics, 2021, 35(7): 103-114.
[8]	DUAN Xuyuan, ZHENG Hongjuan. Research Progress in Modified Poly（lactic acid） Foaming Technology [J]. China Plastics, 2021, 35(7): 134-139.
[9]	YANG Wenjie, HE Jiawen, ZHU Hanbin, WANG Sisi, LI Xiping. Mechanical Properties and Foaming Behaviors of Graphene⁃reinforced Poly（lactic acid） [J]. China Plastics, 2021, 35(6): 26-32.
[10]	SUN Dongbao, LU Qin, LU Xinyu, JIA Wangyi, CAO Shang. Study on Interface Modification Methods and Properties of PLA/Rice Husk Powder Composites [J]. China Plastics, 2021, 35(6): 80-84.
[11]	ZHANG Bo, WANG Xiaofeng, GUO Meng, BAI Zhiyuan, REN Cuihong, HAN Wenjuan, UYAMA Hiroshi, LI Qian. Study on Surface Carboxylation Modification and Cytocompatibility of Poly（Lactic Acid） [J]. China Plastics, 2021, 35(5): 17-23.
[12]	XU Jiayi. Preparation and Properties of Hypromellose⁃toughened Poly（lactic acid） Composites [J]. China Plastics, 2021, 35(5): 59-64.
[13]	CAI Hengfang, SUN Ling. Molecular Dynamics Study on Effects of Temperature and Shear Rate on CO₂ Diffusion Behavior in Foaming Process of Injection Molding [J]. China Plastics, 2021, 35(3): 83-89.
[14]	LUO Fei, HAO Lingao, WANG Tengfei, LIU Hongpeng, DANG Xudan, WANG Yaming, LIU Chuntai, SONG Yan. High⁃temperature Stretching Induced Multi⁃structural Deformation of PLA⁃based Composites [J]. China Plastics, 2021, 35(2): 77-83.
[15]	YIN Peng, MA Hongpeng, GUO Bin, LI Panxin. Thermoplastic starch composites reinforced synergistically with PLA fiber and PVA fiber [J]. China Plastics, 2021, 35(12): 16-20.

Research Progress in Poly ( lactic acid ) -poly ( ethylene glycol)Block Copolymers

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments