中国塑料 ›› 2011, Vol. 25 ›› Issue (04): 17-21 .DOI: 10.19491/j.issn.1001-9278.2011.04.004

• 综述 • 上一篇    下一篇

生物降解性形状记忆聚合物及其在生物医学工程方面的应用

门倩妮 朱光明 许硕贵   

  1. 西北工业大学应用化学系 西北工业大学应用化学系
  • 收稿日期:2010-11-12 修回日期:2010-11-29 出版日期:2011-04-26 发布日期:2011-04-26

Biodegradable Shape Memory Polymers and Their Application in Biomedical Engineering

MENG Qianni ZHU Guangming XU Shuogui   

  • Received:2010-11-12 Revised:2010-11-29 Online:2011-04-26 Published:2011-04-26
  • Contact: ZHU Guangming

摘要: 综述了生物降解性形状记忆聚合物如聚乳酸、聚己内酯、聚氨酯等的最新研究进展及其形状记忆机理。聚乳酸、聚己内酯和聚氨酯分别是通过相态转化、物理或化学交联以及相分离来实现形状记忆特性的。着重讨论了生物降解性形状记忆聚合物在生物医学工程领域的应用研究现状,详述了其在药物缓释、医疗器械、骨组织以及手术缝合线方面的医学应用,并展望了生物降解性形状记忆聚合物今后的发展前景。

关键词: 聚乳酸, 聚己内酯, 聚氨酯, 生物降解, 形状记忆聚合物, 生物医学工程

Abstract: The latest advances in biodegradable shape memory poly(lactide acid), polycaprolactone, and polyurethane were reviewed. The shape memory mechanisms, including phase transforming, physical or chemical cross-linking and phase separation were discussed in briefly. The applications of biodegradable shape memory polymers in drug release, medical instrument, surgery seam, and bone tissue engineering were introduced and discussed. In addition, their trends of development in the future were prospected.

Key words: poly(lactide acid), polycaprolactone, polyurethane, biodegradation, shape memory polymer, biomedical engineering