Preparation and properties of antibacterial biodegradable poly (lactic acid) membrane

doi:10.19491/j.issn.1001-9278.2023.09.002

Abstract

Abstract:

In this study， an antibacterial degradable membrane was successfully prepared through electrostatic spinning using a mixture of quaternary ammonium salt and poly（lactic acid）（PLA）， and their structure and properties were characterized by using scanning electron microscope， electronic universal material testing machine， statistical distribution of fiber diameter， and antibacterial property measurement. The results indicated that the single chain quaternary ammonium salt improve the antibacterial performance of the PLA membrane to a certain extent but reduced its breaking strength and elastic modulus. The double⁃chain quaternary ammonium salt improved the antibacterial performance of the PLA membrane significantly. This ensures that the membrane achieves high tensile/breaking strength and elongation， good membrane formation uniformity， and good dispersity of antibacterial agents. Therefore， the PLA membrane filled with the double⁃chain quaternary ammonium salt is more suitable for industrial production and practical applications.

Key words: quaternary ammonium salt, poly（lactic acid）, electrospinning, antibacterial membrance

CLC Number:

TQ321

GUAN Guotao, LIU Chenze, HE Shiquan, SONG Chaoyang, ZHANG Xiang, ZHAO Na, WANG Chao. Preparation and properties of antibacterial biodegradable poly (lactic acid) membrane[J]. China Plastics, 2023, 37(9): 8-13.

Figures/Tables 5

Fig.1. SEM of different membranes

Fig.2. Fiber diameter distribution of different membranes

Fig.3. Antibacterial properties of different membranes

Fig. 4. Diagram of germicidal mechanism of quaternary ammonium salt

Fig.5. Stress⁃strain curves of different electrospun fibers

References 20

1	张宏博，刘焦萍，赵苏杭，等. 生物可降解塑料发展现状及展望［J］.现代化工， 2023， 43（4）：9⁃17.
	ZHANG H B， LIU J P， ZHAO S H，et al. Development status and prospect of biodegradable plastics［J］. Modern Chemical Industry， 2023， 43（4）：9⁃17.
2	ELSAWY M A， KIM K H， PARK J W， et al. Hydrolytic degradation of polylactic acid （PLA） and its compo⁃sites［J］. Renewable & Sustainable Energy Reviews， 2017， 79（11）：1 346⁃1 352.
3	MA K， MEI D， LIN X， et al. A synthetic biodegradable polymer membrane for guided bone regeneration in bone defect ［J］. J Biomed Nanotechnol， 2021， 17（3）： 456⁃465.
4	ZHU T， CHEN S， LOU J， et al. Preparation and properties of PLA / PDMS composite membranes for oxygen⁃enrichment membrane ［J］. Bulletin of the Chinese Ceramic Society， 2014， 33（12）： 3 304⁃3 309.
5	陈晨伟，汪浩东，刘昌树，等. PLA抗菌/抗氧化活性包装薄膜在食品中的应用及其安全性评价［J］. 中国塑料， 2023， 37（3）：52⁃63.
	CHEN C W， WANG H D， LIU C S，et al. Applications and safety evaluation of PLA antibacterial /antioxidant active films for foodpackaging［J］.China Plastics， 2023， 37（3）：52⁃63.
6	SATTI S M， ABBASI A M， SALAHUDDIN， et al. Statistical optimization of lipase production from Sphingobacterium sp. strain S2 and evaluation of enzymatic depolymerization of Poly（lactic acid） at mesophilic temperature［J］. Polymer Degradation and Stability， 2019， 160：1⁃13.
7	范少华. PBAT/PLA可降解地膜老化性能研究［D］. 山东农业大学， 2020.
8	ZAABA N F， JAAFAR M， A review on degradation mechanisms of polylactic acid： hydrolytic， photodegradative， microbial， and enzymatic degradation［J］. Polymer Engineering and Science， 2020， 60 （9）： 2 061⁃2 075.
9	MERLETTINI A， PANDINI S， AGNELLI S， et al. Facile fabrication of shape memory poly（ε⁃caprolactone） non⁃woven mat by combining electrospinning and sol–gel reaction［J］. RSC Advances， 2016， 6（50）：43 964⁃43 974.
10	赵沐涵. 季铵盐型阳离子聚合物的合成及其灭菌活性研究［D］. 西北大学， 2020.
11	张伟，许君，巩继贤，等. 基于季铵盐抗菌抗病毒纺织品研究现状及展望［J］.针织工业， 2023， 408（1）：84⁃89.
	ZHANG W， XU J， GONG J X， et al. Research progress of antibacterial and antiviral textiles based on quaternary ammonium salt［J］. Knitting Industries， 2023， 408（1）：84⁃89.
12	YE X， SHI Q， TAN S. Preparation of graphene oxide/dodecyl dimethyl benzyl ammonium chloride complex and its antibacterial properties ［J］. Industrial Microbiology， 2016， 46（4）： 49⁃52.
13	XIE R F， HU Q F， YANG G Y， et al. Solid⁃phase extraction gold from alkaline cyanide solution with quaternary ammonium surfactant ［J］. Rare Metals， 2016， 35（3）： 282⁃288.
14	张耀成，吴勇振，李阳，等. 双季铵盐改性医用PVC抗菌材料［J］. 中国塑料， 2021， 35（7）： 53⁃57.
	ZHANG Y C， WU Y Z， LI Y， et al. Gimini Quaternary Ammonium Salt⁃modified PVC⁃based Antibacterial Materials for Medical Use ［J］. China Plastics， 2021， 35（7）： 53⁃57.
15	吴威. 抗菌医用PVC材料的制备［D］；北京化工大学， 2019.
16	周丽佳. 载顺铂联合氯喹聚乳酸静电纺丝膜对口腔癌CAL-27细胞的杀伤作用研究［D］. 吉林大学， 2015.
17	LIU Y， WANG S， ZHANG R， et al. Development oo poly（lactic acid）/chitosan fibers loaded with essential oil for antimicrobial applications［J］. Nanomaterials， 2017， 7（7）：194.
18	DING J， DWIBEDI V， HUANG H， et al. Preparation and antibacterial mechanism of cinnamaldehyde/tea polyphenol/polylactic acid coaxial nanofiber films with zinc oxide sol to shewanella putrefaciens［J］. International Journal of Biological Macromolecules，2023， 237： 123932.
19	邵琳颖，郗悦玮，翁云宣. 可降解聚乳酸复合材料研究进展，中国塑料， 2022， 36（6）：155⁃164.
	SHAO L Y， XI Y W， WENG Y X. Research progress in degradation characteristics of poly（lactic acid） composites［J］. China Plastics， 2022， 36（6）：155⁃164.
20	Mazur K， Singh R， Friedrich R P， et al. The effect of antibacterial particle incorporation on the mechanical properties， biodegradability， and biocompatibility of PLA and PHBV composites［J］. Macromol Mater Eng， 2020， 305（9）：2000244.

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